Description
MethoxyPEGSuccinimidylHexanoatewithsuperiorqualityspecificationof ≥95%Substitution.
JenKemTechnology’sMethoxyPEGSuccinimidylHexanoate (MethoxyPEGSHA)isahighqualityaminereactivePEGproductwithastablenon-degradablelinkerbetweenthePEGpolymericchainandtheNHSester.MethoxyPEGSuccinimidylHexanoate reactswiththeaminegroupoflysine(s)atpH7-8.MethoxyPEGSuccinimidylHexanoatehasa longerhydrolysishalf-lifecomparedwithM-PEG-SCMandM-PEG-SBA.JenKemTechnologyoffersMethoxyPEGSHA withMW5000Da(M-SHA-5000),andMW20000Da(M-SHA-20K),in1gand10gpackingsizes.
DifferentMWofMethoxyPEGSHA productsmaybeavailablebycustomsynthesis,pleaseemailus attech@jenkemusa.comfordetailsoncustomPEGs.OtherlinearJenKemNHSesterPEGsareavailable–ifinterestedpleaseselectstablelinkerNHSPEGs,carbonatelinkerstableNHSPEGs,or cleavablelinkerNHSPEGs.JenKemTechnology providesrepackagingservicesforanadditionalfee,pleasecontactusifyourequireadifferentpackagesizethanourcatalogselection.
BulkPEGsandGMPgradePEGsaremade-to-order.Pleasecontactus forbulkpricing.
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References:
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2.Look,L.,etal.,Ligand-ModifiedHumanSerumAlbuminNanoparticlesforEnhancedGeneDelivery,MolecularPharmaceutics, 2015,12(9),3202-3213.
3.FahrlanderE.,etal.,PEGylatedhumanserumalbumin(HSA)nanoparticles:preparation,characterizationandquantificationofthePEGylationextent, Nanotechnology,2015,26(14):145103.
4. Gossmann,R.,etal.,ComparativeexaminationofadsorptionofserumproteinsonHSA-andPLGA-basednanoparticlesusingSDS–PAGEandLC–MS,EuropeanJournalofPharmaceuticsandBiopharmaceutics,2015,93,p.80-87.
Foundedin2001byexpertsinPEGsynthesisandPEGylation,JenKemTechnologyspecializesexclusivelyinthedevelopmentandmanufacturingofhighqualitypolyethyleneglycol(PEG)productsandderivatives,andrelatedcustomsynthesisandPEGylationservices.JenKemTechnologyisISO9001andISO13485certified,andadherestoICHQ7AguidelinesforGMPmanufacture.TheproductionofJenKem®PEGsisback-integratedtoin-housepolymerizationdirectlyfromethyleneoxide,enablingfaciletraceABIlityforregulatedcustomers.JenKemTechnologycaterstothePEGylationneedsofthepharmaceutical,biotechnology,medicaldeviceanddiagnostics,andemergingchemicalspecialtymarkets,fromlaboratoryscalethroughlargecommercialscale.
